Your Location：Home > Products > Pharmaceutical intermediates >3685-84-5
Product Details
|
Pharmacological action |
Meclofenoxate hydrochloride(MecloCl) [CAS,NO:51-68-3], an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition. Meclofenoxate hydrochloride is a psychostimulant in the nootropic agent group available in capsule and tablet formulations approved for traumatic cataphora, alcoholic poisoning, anoxia neonatorum, and children's enuresis in China. Although these 2 generic formulations are marketed in China, information regarding their pharmacokinetics and bioequivalence in humans has not been published. Meclofenoxate hydrochloride appears to increase the consolidation of new information into long-term memory. Meclofenoxate does not affect other aspects of remembering. Meclofenoxate is found that significantly more of the subjects receiving meclofenoxate reportes an increased level of mental alertness. |
|
Safety Profile |
Poison by intravenous route.Moderately toxic by ingestion and intraperitoneal routes.When heated to decomposition it emits very toxic fumes ofCl??, NOx, and HCl. |
InChI:InChI=1/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H
The invention discloses a meclofenoxate ...
Herbicidal ionic liquids (HILs) constitu...
-
2-(N,N-dimethylamino)ethanol
4-chlorophenyloxyacetyl chloride
meclofenoxate hydrochloride
| Conditions | Yield |
|---|---|
|
In
chloroform;
|
90% |
|
With
benzene;
Behandeln des Reaktionsprodukts mit Chlorwasserstoff in Aether und Aceton;
|
|
|
2-(N,N-dimethylamino)ethanol; 4-chlorophenyloxyacetyl chloride;
In
dichloromethane;
at 20 ℃;
Green chemistry;
With
hydrogenchloride;
In
ethyl acetate;
Solvent;
Green chemistry;
|
68 g |
4-Chlorophenoxyacetic acid
meclofenoxate hydrochloride
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: SOCl2
2: benzene / Behandeln des Reaktionsprodukts mit Chlorwasserstoff in Aether und Aceton
With
thionyl chloride; benzene;
|
|
|
Multi-step reaction with 2 steps
1: thionyl chloride / 2 h / 75 °C
2: chloroform
With
thionyl chloride;
In
chloroform;
|
2-(N,N-dimethylamino)ethanol
4-chlorophenyloxyacetyl chloride
4-Chlorophenoxyacetic acid
2-(N,N-dimethylamino)ethanol
4-Chlorophenoxyacetic acid
2-(N,N-dimethylamino)ethanol hydrochloride
meclofenoxate
CAS：839712-12-8
CAS：153-98-0
CAS：175481-36-4?
CAS：608-07-1
