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Quality products make an important contribution to long-term revenue and profitability. Factory Sells Best Quality (S)-3-Hydroxy-gamma-butyrolactone 7331-52-4 with stock
(S)-3-Hydroxy-γ-butyrolactone can be used as an anticancer drug resistance inhibitor.
but-3-enoic acid
4-Hydroxy-dihydro-furan-2-on
| Conditions | Yield |
|---|---|
|
With
dihydrogen peroxide;
In
tert-butyl alcohol;
|
91% |
|
With
osmium(VIII) oxide; barium chlorate; water;
|
|
|
With
Perbenzoic acid; chloroform;
|
4-chloro-3-hydroxybutylamide
4-Hydroxy-dihydro-furan-2-on
| Conditions | Yield |
|---|---|
|
In
water; butanone;
at 60 ℃;
for 24h;
|
92% |
|
In
water;
at 70 ℃;
for 3h;
|
65.2% |
|
In
water;
at 30 - 100 ℃;
for 0.5 - 336h;
pH=1.2 - 5.5;
Aqueous phophate buffer;
|
56.5% |
The CAS number of (S)-3-Hydroxy-gamma-butyrolactone is 7331-52-4.
More information of (S)-3-Hydroxy-gamma-butyrolactone 7331-52-4 are:
|
CAS Number |
7331-52-4 |
|
Density |
1.393 g/cm3 |
|
Melting Point |
1.24ºC |
|
Boiling Point |
310.3 °C at 760 mmHg |
|
Flash Point |
157 °C |
|
Vapor Pressure |
5.42E-05mmHg at 25°C |
|
Refractive Index |
n20/D 1.464(lit.) |
|
HS CODE |
29322090 |
|
PSA |
46.53000 |
|
LogP |
-0.70580 |
|
Pka |
12.87±0.20(Predicted) |
Synonyms for (S)-3-Hydroxy-gamma-butyrolactone 7331-52-4:2(3H)-Furanone,dihydro-4-hydroxy-, (S)-;Butyric acid, 3,4-dihydroxy-, g-lactone, D-glycero- (8CI);(3S)-Hydroxy-g-butyrolactone;(S)-(-)-b-Hydroxy-g-butyrolactone;(S)-3-Hydroxy-g-butyrolactone;(S)-3-Hydroxybutyrolactone;(S)-b-Hydroxy-g-butyrolactone;
The chemical formula of (S)-3-Hydroxy-gamma-butyrolactone is C4H6O3 which containing 4 Carbon atoms,6 Hydrogen atoms and 3 Oxygen atoms,and the molecular weight of (S)-3-Hydroxy-gamma-butyrolactone is 102.09.
(S)-3-Hydroxy-gamma-butyrolactone is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S-oxiracetam (S-ORC). It can be deoxidized to (S)-(+)-3-Hydroxytetrahydrofuran which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer.
InChI:InChI=1/C4H6O3/c5-3-1-4(6)7-2-3/h3,5H,1-2H2/t3-/m0/s1
Relevant articles related to (S)-3-Hydroxy-gamma-butyrolactone:
|
Article |
Source |
|
Synthesis of nature product kinsenoside analogues with anti-inflammatory activity |
Song, Wei,Sun, Yong,Xu, Lintao,Sun, Yajing,Li, Tianlu,Peng, Peng,Lou, Hongxiang supporting information, (2020/12/02) |
|
Synthesis method of R-3-propyl-gamma-butyrolactone |
- Paragraph 0042; 0045-0048, (2020/07/12) |
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